In mathematics, Voronoi diagram is partitioning of a plane into regions based on the distance to points in a specific subset of the plane. That set of points(called seeds, sites, or generators) is specified beforehand and for each seed, there is a corresponding region consisting of all points closer to that seed than to any other. These regions are called Voronoi cells. The Voronoi diagram of a set of points is dual to its Delaunay triangulation. In biology, Voronoi diagrams are used to model number of different biological structures, including cells and bonr microarchitecture. Indeed, Voronoi tessellations work as a geometrical tool to understand the physical constraints that drive the organization of biological tissues.